SICB Division of Comparative Endocrinology (DCE)

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From the DCE Researchers Database

Robert John Denver Hormone action in animal development

We study hormone action in animal development. Much of our research focuses on animals with complex life cycles (i.e., metamorphosing amphibians) because they provide unique opportunities to study the molecular basis for hormone action, environmental effects on development (phenotypic plasticity) and life history evolution. We are interested in how the environment influences the production of neurohormones, and consequently how neurohormones control the stress and thyroid axes. We also investigate the molecular mechanisms by which stress (corticosteroid) and thyroid hormones influence development of the brain and pituitary gland, and the long-term phenotypic consequences (neural, physiological and behavioral) of exposure to stress hormones early in life. Our research is multidisciplinary, spanning cellular and molecular biology, neurobiology, development, ecology and evolution. Denver Lab Homepage: http://www.mcdb.lsa.umich.edu/labs/denver/