Meeting Abstract

95.4  Saturday, Jan. 7  Influence of Polychlorinated Biphenyls on Gene Expression and Corticosteroid Secretion within the Neuroendocrine Stress System of the red-eared slider turtle, Trachemys scripta elegans THOMPSON, JT*; VALVERDE, RA; Southeastern Louisiana University; Southeastern Louisiana University

In order to adequately address anthropogenic environmental degradation, it is necessary to the physiological effects experienced by biota present in the impacted area. Of particular interest is the introduction of bioactive compounds, such as polychlorinated biphenyls (PCBs), which have been shown to disrupt growth and development of the reproductive and nervous systems. The influence of these compounds on the endocrine stress response has yet to be described. The vertebrate ability to maintain homeostasis in response to a stressor is mediated by the neuroendocrine stress system (NSS). The purpose of this study was to determine the effects of PCB exposure on the NSS by quantifying expression of thyroid stimulating hormone (TSH) and pro-opiomelanocortin (POMC), as well as plasma concentrations of corticosterone (CORT) in response to prolonged immobilization stress.